Reported in Nature Materials, we demonstrate the use of atomic force microscopy (AFM)-based single molecule force spectroscopy (SMFS) to quantitatively derive the energy landscape of modular rupture and refolding of our titin-mimicking polymer. This is the first example of a direct correlation between nano-mechanical properties and bulk mechanical performance using the energy landscape derived from SMFS. The report demonstrates the potential for SMFS to serve as a guide for rational design of advanced multifunctional materials.


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8/21/15 Congratulations to James and Hannah on your marriage, and best wishes for a happy life together forever.

8/14/15 Our collaboration with Prof. Bert Meijer's group on forced unfolding of single-chain nanoparticle was highlighted by Nature Chemistry. Congrats to the joint team!

8/4/15 Congrats to Mark, Hanxiang, and Nate for the acceptance of the paper on bolaamphiphiles for siRNA delivery by ACS Central Science. Fantastic work!

7/22/15 Zhibin was appointed as a CAS Overseas Expert by the Chinese Academy of Science.

7/16/15 Congrats to Jae for being awarded the Allergan Graduate Fellowship. Well deserved!

7/14/15 Zhibin delivered a Speech at the graduation ceremony of the College of Chemistry and Molecular Engineering, Peking University, China.

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