Good-bye to Su-Ho, and Hello to Yong-Jin on June 29. With (from left) Professor Il-Doo Kim (KAIST), Reg, Su-Ho Cho, and Yong-Jin Jeong, (both of KAIST). The fist symbolizes something at KAIST.

An Impedance-Transduced Chemiresistor with a Porous Carbon Channel for Rapid, Nonenzymatic, Glucose Sensing
Alana F. Ogata, Seok-Won Song, Su-Ho Cho, Won-Tae Koo, Ji-Soo Jang, Yong Jin Jeong, Min-Hyeok Kim, Jun Young Cheong, Reginald M. Penner*, Il-Doo Kim*

Analytical Chemistry (2018) Just Accepted.

Alana has developed a new type of chemiresistor, the impedance-transduced chemiresistor (ITCR), for the rapid analysis of glucose. The ITCR exploits porous, high surface area, fluorine-doped carbon nanofibers prepared by electrospinning of fluorinated polymer nanofibers followed by pyrolysis. These nanofibers are functionalized with a boronic acid receptor and stabilized by Nafion enabling glucose detection. The recognition and binding of glucose by the ITCR is detected by measuring its electrical impedance at a single frequency.

Good-bye Lunch for Hiro and Su-Ho, and welcome lunch for Yong Jin at BDC Tofu House in Irvine, June 28, 2018. Clockwise from lower left: Hiro, Alana, Vivian, Shaopeng, Ilektra, Eric, Yong Jin, Reg, Su-Ho, and Annee. (missing: Josh (making nanowires!), Gaurav, Ray, Thien, Apurva, Undral, Christine, Prof. Il-Doo Kim).

Hierarchical Hierarchical Metal-Organic Framework Assembled Membrane Filter for Efficient Removal of Particulate Matter
Won-Tae Koo, Ji-Soo Jang, Shaopeng Qiao, Wontae Hwang, Gaurav Jha, Reginald M. Penner, and Il-Doo Kim*

ACS Appl Mater Inter 10 (2018) 19957.

Metal-organic frameworks or MOFs can function as efficient particulate filters. The assembly of two-dimensional (2D) Zn-based zeolite imidazole frameworks (2D-ZIF-L) in deionized water over a period of time produced hierarchical ZIF-L (H-ZIF-L) on hydrophilic substrates. Won-Tae and his coworkers demonstrated H-ZIF-L-assembled polypropylene microfibers as a washable membrane filter with highly efficient PM removal property (92.5 +/- 0.8% for PM2.5 and 99.5 +/- 0.2% for PM10), low pressure drop (10.5 Pa at 25 L/min), long-term stability, and superior recyclability. These outstanding particle filtering properties are mainly attributed to the unique structure of the 2D-shaped H-ZIF-L, which is tightly anchored on individual fibers comprising the membrane.

The Virus BioResistor: Wiring Virus Particles for the Direct, Label-Free Detection of Target Proteins
Apurva Bhasin, Alana F. Ogata, Jeffrey S. Briggs, Phillip Y. Tam, Ming X. Tan, Gregory A. Weiss*, Reginald M. Penner*
Nano Letters 18 (2018) 3623.

As co-first authors, Apurva and Alana have invented the virus bioresistor (VBR) which is a chemiresistor that directly transfers information from virus particles to an electrical circuit. Specifically, the VBR enables the label-free detection of a target protein that is recognized and bound by filamentous M13 virus particles, each with dimensions of 6 nm (w) x 1 micron (l), entrained in an ultrathin (250 nm) composite virus - polymer resistor. The VBR concept is demonstrated using a model system in which human serum albumin (HSA, 66 kDa) is detected in a phosphate buffer solution. The resistance change induced by HSA binding is as high as 200 Ohms, contributing to low sensor-to-sensor coefficients-of-variation (<15%) across the entire calibration curve for HSA from 7.5 nM to 900 nM. The response time for the VBR is 3 - 30 s.

Friday, March 2, 2018
Alana (at right) wins the UCI GradSlam! with her talk, ``The Future of Early Detection: An at Home Cancer Test'' Now, it's on to the UC-Wide Grad-Slam competition on May 3! Congrats Alana!! (photo credit: Gaurav Jha).

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