Applications of Neutron Scattering in Structural Biology and Biophysics

A symposium to be held at the 2002 American Chemical Society National Meeting in Boston, Massachussetts, August 18-22, 2002

Purpose and scope of the symposium:

Neutrons produced by present research-oriented sources typically have wavelengths on the order of Angstroms, and energies of tens of wavenumbers, and hence are well-suited for probing the structures and motions of molecules. Neutrons scatter from nuclei, both coherently and incoherently. Coherent scattering provides information on structure and collective dynamics, and incoherent scattering on single particle motion. The large difference in scattering cross-sections between hydrogen and deuterium provides a powerful method for accentuating (or masking) the scattering from particular parts of a system by selective deuteration. Neutron scattering has been demonstrated to be a powerful tool for characterizing the structures and dynamics of biological molecules. In light of the on-going planning and construction of new neutron sources worldwide with unprecedented capabilities (e.g. the Spallation Neutron Source in the U. S. and the European Spallation Source in Europe), it is anticipated that biological applications of neutron scattering will continue to increase.

The goals of this symposium are to showcase the unique insight that neutron scattering can provide into the structure and function of biomolecules, and outline directions for future applications of new sources and instruments to biological problems. We also wish to attract structural biologists and biophysicists who have not had direct experience with neutron scattering to consider it as a valuable research tool, and to help define problems that could benefit from the unique capabilities of using neutrons as probes. Speakers will be invited to present recent results of applications of a wide variety of neutron scattering measurements (protein and membrane diffraction, reflectometry, small-angle scattering for structure; quasi-elastic scattering, spin echo, and vibrational spectroscopy for dynamics), as well as theoretical molecular models for interpreting the data.

If you are an invited speaker and you have not yet submitted the abstract of your talk, or if you wish to participate in the symposium by giving a contributed talk and/or presenting a poster, please following the directions given here. The deadline for submitting abstracts is Friday, March 22, 2002. If you have any questions concerning this symposium that are not answered on this web site, please do not hesitate to contact one of the organizers:

Douglas Tobias (dtobias@uci.edu)
Mounir Tarek (tarek@lctn.uhp-nancy.fr)

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