The Prescher Lab

Expanding the imaging toolkit to spy on cellular communication

Our research team is crafting novel probes to "spy" on cells and decipher their communications in vivo. Cellular networks drive diverse aspects of human biology, ranging from immune function to memory formation. Breakdowns in these networks also underlie numerous pathologies. While cell-cell interactions play key roles in human health and disease, the mechanisms by which cells transact information in vivo are not completely understood. The number of cells types involved, the timing and location of their interactions, the molecular cues exchanged, and the long-term fates of the cells remain poorly characterized in most cases. We are designing and deploying custom tools to visualize cellular networks in real time—and with molecular precision—in physiologically relevant environments. Collectively, our work is decoding cellular communications relevant to infectious disease, cancer metastases, and immune function.

News and Events

April 2020

  • Mariana was named an NSF GRFP fellow! Congratulations!

March 2020

  • Dr. Alicia Mangubat-Medina (Rice University) joins the lab as a postdoctoral fellow. Welcome!

February 2020

  • Graduate students Zach, Kat, and Sharon joined the lab. Welcome!

January 2020

  • Undergraduate Meghan Dyck joins the lab. Welcome to the team!
  • Undergrads Sabrina, Buvan, Elena, Clare, Landon, Jonathan, Steve, and Jenny were all awarded UROP Fellowships for their research projects! Keep crushing it guys!