Dr. Wolfe is a Mathias P. Mertes Professor of Medicinal Chemistry at the University of Kansas. His research career has been dedicated to elucidating the molecular basis of Alzheimer’s disease (AD). Awards for his work include a Zenith Award from the Alzheimer’s Association, the MetLife Award for Biomedical Research, and the Potamkin Prize from the American Academy of Neurology. His lab has been especially focused on the γ-secretase complex, a protease that plays central roles in Alzheimer pathogenesis.