Interactions of molecules in the electronically excited state play a key role for a number of photophysical effects, here we are particularly concerned with exciplex formation and energy transfer processes. These effects, in turn, are important for the understanding of exciton diffusion in e.g. the light harvesting complex of green plants or in organic semiconductors[1]. Quantumchemical calculations help to get an atomistic understanding of the factors that influence these processes. In this contribution we review our recent research projects in this area.

Materials have historically been developed for a wide variety of applications by a largely empirical process, sometimes referred to as an Edisonian or observation and validation approach. Scientists worldwide have long sought to develop new materials in a reverse process where one specifies performance and then designs a material to meet a set of criteria using predictive computational and simulation tools along with sophisticated and precise laboratory control in the material fabrication stage.

Electrically switchable DNA layers for the label-free detection and sizing of protein targets on a chip Ulrich Rant Walter Schottky Institute, Technical University Munich We introduce a chip-compatible scheme for the label-free detection of proteins in real- time that is based on the electrically driven conformation-switching of DNA oligonucleotides on metal surfaces. The switching behavior is a sensitive indicator for the specific recognition of IgG antibodies, antibody-fragments, and small proteins, which can be detected in quantities of less than 1 amol on the sensor surface.

Abstract: In this talk fundamentally new imaging and detection architectures will be introduced that can compensate in the digital domain for the lack of complexity of optical components by use of novel theories and numerical algorithms to address the immediate needs and requirements of Telemedicine for Global Health Problems.