Tobias group simulations help reveal the allosteric mechanism of water-channel gating by Ca++-calmodulin

In the September issue of Nature Structural and Molecular Biology 
the Tobias group, the Hall lab at UCI, and the Gonen lab at the 
Janelia Farm Research Campus report a combined experimental and 
computational study that elucidates the mechanism of calcium regulation 
of water conduction by the membrane protein channel aquaporin 0.