Tuesday, October 25, 2011

Grads Ruminski, Webb, and  Riccitelli from the Luptak lab find the first self-cleaving ribozymes that translate downstream sequences.

Self-cleaving ribozymes are typically used for processing of long RNA transcripts. In a recent publication, graduate students Dana Ruminski, Judy Webb and Nate Riccitelli from the Luptak group, reveal that one family of these catalytic RNAs also promotes translation of downstream sequences - a first for a ribozyme - and may also protect the RNAs from cellular insults.

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