Sunday, August 2, 2015

Prescher group built a `caged' Luciferin for imaging cell–cell contacts. A recent JACS communication describes a new method for imaging cell-cell communication.  

The approach relies on a caged luciferin molecule that is selectively released by one cell, then selectively consumed by a neighboring cell.  This strategy will enable numerous cell-cell interactions relevant to organismal biology and disease to be visualized in vivo.