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Friday, February 18, 2022
Congratulations to the Jarvo research group for being awarded the 2021 SYNLETT Best Paper Award for their article "Nickel-Catalyzed Cross-Electrophile Coupling of the Difluoromethyl Group for Fluorinated Cyclopropane Synthesis."
In their brilliant work, Erika L. Lucas, Tristan M. McGinnis, Anthony J. Castro and Elizabeth R. Jarvo have invented a conceptually new approach to fluorinated cyclopropanes. It is based on a photocatalytic styrene methoxy difluoromethylation, the products of which are elegantly used in a nickel-catalyzed intramolecular cross-electrophile coupling reaction between the difluoromethyl moiety and the methyl ether. This work is highly creative and timely and an excellent example what SYNLETT readers can expect.