Abstract:

In the past couple of decades, most of the research efforts of our group have been dedicated to the functionalization of non-activated C(sp3)–H and C(sp2)–H bonds using catalysis by palladium(0) complexes.1 In recent years, we have developed enantioselective versions of such reactions by employing different types of chiral catalysts (ancillary ligand,2 base3 or bifunctional system4), which enable the control of various stereogenic elements (center,5 axis,6 helix7).8 This lecture will present our latest results in this rapidly developing field.

Bio:

Olivier Baudoin was educated in ENSC Paris and obtained his PhD degree in 1998 under the supervision of Prof. J.-M. Lehn and Dr. M.-P. Teulade-Fichou at Collège de France, Paris. After a post-doc with K. C. Nicolaou at the Scripps Research Institute, La Jolla (USA), he was recruited as CNRS researcher at the Institut de Chimie des Substances Naturelles (France) in 1999, where he became an independent group leader in 2004. In 2006, he was appointed as Professor at the University of Lyon and since 2015 he has been a Full Professor at the University of Basel (Switzerland). Since 2021, he has been heading the chemistry department. He received the CNRS Bronze Medal in 2005, the Young Professor Award from the French Chemical Society, Organic Chemistry Division in 2010, and was a Junior Member of the Institut Universitaire de France from 2009-2014. His current research focuses on the development of new methods for the functionalization of C–H bonds and their application to complex molecule synthesis.