Abstract: Chemistry, for many researchers, ends with distinguishing element from element. Stable isotopes, physically separated from one another as further divisions of the elements, extends the range of research possibilities. After the isotope separation process, these enriched isotopes are further purified chemically then stored in their most stable chemical form.

Abstract: While allostery has been a topic of intense interest for the past several decades, our understanding of the underlying mechanism at the molecular level continues to be challenged by new experimental observations. Specifically, a recent deep mutational scanning study of a bacterial transcription factor TetR found that allostery hotspot residues are broadly distributed over a major portion of the protein structure, rather than being clustered near the ligand-binding and DNA-binding domain interfaces as often discussed in structure-based studies.

Machine learning is transforming many aspects of people's lives at an extraordinary rate, as shown by the appearance and adoption of large language models, such as chatGPT. It is (at a slower and less successful rate) showing up in physical sciences, appearing in up to 10% of new papers in some areas. Some of these papers are excellent, while many do not meet traditional scientific publishing standards.

Abstract: A nanoparticle (NP) entering the human body results in the formation of a nano-bio interface in which a variety of proteins play a major role, forming a nanoparticle protein corona (NPC). Recently, studies of the NPC’s biophysical properties have become a major area of research. It is important to understand, characterize and model the biophysical properties and the molecular interactions related to NPCs in biological environments. Understanding these processes should be achieved at a detailed atomic level, however, molecular studies of NPC models are lacking.