Events in organic chemistry.

Asymmetric Catalysis and its Application towards the Development of an Ideal Synthesis for BI’s 11β-HSD 1 Inhibitor

Abstract: During the past few decades, active pharmaceutical ingredients are becoming increasingly complex and costly to synthesize. Development of sustainable, greener and economically viable manufacturing processes is demanding. Asymmetric catalytic transformations with the aid of chiral phosphine ligands have played a critical part for API development.

Enantioselective Chemical Synthesis Methods via Cooperative Catalysis: Design, Development and Application

Abstract: Our laboratory has embraced cooperative catalysis as a general framework for the design of new enantioselective reactions. Within this regime we have exploited cooperative Lewis base/transition metal catalysis as an effective means to control and direct both reaction partners during  bond construction.


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