Liquid cell transmission electron microscopy (LC-TEM) has emerged as a powerful tool for direct visualization of nanocrystal nucleation and growth at high spatial resolution. Current limitations of the liquid cell sample holders necessitate utilizing the electron beam as the stimulus for initiating nanocrystal formation and other related processes like molecular crystallization, nanoparticle etching, and self-assembly. Electron beam induced chemistry has proven to be considerably more complex than conventional chemical reagents used in flask-based synthesis of nanomaterials.